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只有pick sb up一种说法，pick up 接乘,搭载.其中up是副词,故代词做宾语只能居中。区别在于pick up是一个动词词组，而pick-up是一个单词，其他并无区别。pick up 改善、好转、增强；重新开始、继续；收拾、整理；接电话。
pick sb up的不同含义
一、捡起
He picked his cap up from the floor and stuck it back on his head.
他从地板上捡起帽子，重新戴在头上。
二、（贸易、经济）改善
Industrial production is beginning to pick up.
工业生产正在开始好转。
三、收拾
She was going over to her parents' house to pick up some clean clothes for Oskar.
她正要去父母家为奥斯卡收拾几件干净的衣服。
四、学会
Where did you pick up your English?
你是在哪儿学得英语？
五、逮捕
Rawlings had been picked up by police at his office.
罗林斯在他的办公室被警察逮捕了。
pick 的相关短语
1、pickup on：v.与...熟悉起来。
2、pickup：v. 改善；好转；增强；重新开始；振作精神；继续；(为某人)收拾，整理；接人；把(人或东西)带走；捡起，收集，得到；偶然结识；站起；学会。
3、topickup：偷。
4、pickup with：结识，认识……
5、pickonsb：作弄某人, 惹恼某人, 挑中, 选中。
6、pickoneself up：重新爬起来。
7、pickup the tab：付帐，承担费用。
8、pickme up：含酒精的饮料，提神的酒。
9、pick on someone：批评别人，或者是欺负别人。